Total synthesis of the Isodon diterpene sculponeatin N.
نویسندگان
چکیده
The total synthesis of sculponeatin N, a bioactive polycyclic diterpene isolated from Isodon sculponeatus, is reported. Key features of the synthesis include diastereoselective Nazarov and ring-closing metathesis reactions, and a highly efficient formation of the bicyclo[3.2.1]octane ring system by a reductive radical cyclization.
منابع مشابه
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ورودعنوان ژورنال:
- Angewandte Chemie
دوره 53 11 شماره
صفحات -
تاریخ انتشار 2014